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Article

Identification and mutational analysis of bacteriophage PRD1 holin protein P35.

Journal of bacteriology - 1 Jul 2003

Rydman Pia S, Bamford Dennis H

Abstract excerpt

Holin proteins are phage-induced integral membrane proteins which regulate the access of lytic enzymes to host cell peptidoglycan at the time of release of progeny viruses by host cell lysis. We describe the identification of the membrane-containing phage PRD1 holin gene (gene XXXV). The PRD1 holin protein (P35, 12.8 kDa) acts similarly to its functional counterpart from phage lambda (gene S), and the defect in...

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Identifiers

PMID: 12813073
DOI: 10.1128/JB.185.13.3795-3803.2003
PMCID: PMC161566

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Source receipt: pubmed, retrieved 7 Sept 2026.

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