Article
Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein.
The Journal of cell biology - 6 Apr 1998
Harada A, Takei Y, Kanai Y, Tanaka Y, Nonaka S, Hirokawa N
Abstract excerpt
Cytoplasmic dynein, a minus end-directed, microtubule-based motor protein, is thought to drive the movement of membranous organelles and chromosomes. It is a massive complex that consists of multiple polypeptides. Among these polypeptides, the cytoplasmic dynein heavy chain (cDHC) constitutes the...
Topics
- Animals
- Base Sequence
- Blastocyst
- Cells, Cultured
- DNA Primers
- Dyneins
- Embryonic and Fetal Development
- Genotype
- Golgi Apparatus
- Heterozygote
- Lysosomes
- Mice
- Mice, Knockout
- Molecular Sequence Data
- Phenotype
- Polymerase Chain Reaction
- Rats
- Sequence Alignment