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Targeting NF-κB-Inducing Kinase (NIK) in Immunity, Inflammation, and Cancer

11 Nov 2020

Abstract excerpt

NF-κB-inducing kinase (NIK), the essential upstream kinase, which regulates activation of the noncanonical NF-κB pathway, has important roles in regulating immunity and inflammation. In addition, NIK is vital for maintaining cellular health through its control of fundamental cellular processes, including differentiation, growth, and cell survival. As such aberrant expression or regulation of NIK is associated...

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PMID: 33187137
DOI: 10.3390/ijms21228470

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