Article
Long L1 insertions in human gene introns specifically reduce the content of corresponding primary transcripts.
Genetica - 1 Jan 2000
Ustyugova Svetlana V, Lebedev Yuri B, Sverdlov Eugene D
Abstract excerpt
LINE-1 (L1) retrotransposons comprise about 17% of the human genome and include a recently transposed set of Ta-L1 elements that are polymorphic in humans. Although it is widely believed that L1s play an essential role in shaping and functioning of mammalian genomes, the understanding of the impa...
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