Article
Role of the 3' splice site in U12-dependent intron splicing.
Molecular and cellular biology - 1 Mar 2001
Dietrich R C, Peris M J, Seyboldt A S, Padgett R A
Abstract excerpt
U12-dependent introns containing alterations of the 3' splice site AC dinucleotide or alterations in the spacing between the branch site and the 3' splice site were examined for their effects on splice site selection in vivo and in vitro. Using an intron with a 5' splice site AU dinucleotide, any nucleotide could serve as the 3'-terminal nucleotide, although a C residue was most active, while a U residue was...
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