Article
Exogenous surfactant changes the phenotype of alveolar macrophages in mice.
American journal of physiology. Lung cellular and molecular physiology - 1 Apr 2001
Kramer B W, Jobe A H, Ikegami M
Abstract excerpt
Alveolar macrophages are essential for the maintenance of surfactant homeostasis. We asked whether surfactant treatment would change alveolar macrophage number and whether the alveolar macrophage phenotype would become activated or apoptotic when challenged in vivo with exogenous surfactant. Surfactant pool size in mice was increased by repetitive surfactant treatments containing 120 mg/kg (110 micromol/kg)...
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