Article
Maintenance of human amnion epithelial cell phenotype in pulmonary surfactant.
Stem cell research & therapy - 4 Sept 2014
McDonald Courtney A, Melville Jacqueline M, Polglase Graeme R, Jenkin Graham, Moss Timothy J M
Abstract excerpt
INTRODUCTION: Preterm newborns often require mechanical respiratory support that can result in ventilation-induced lung injury (VILI), despite exogenous surfactant treatment. Human amnion epithelial cells (hAECs) reduce lung inflammation and resultant abnormal lung development in preterm animals; co-administration with surfactant is a potential therapeutic strategy. We aimed to determine whether hAECs remain...
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