Article
Differential effect of surfactant and its saturated phosphatidylcholines on human blood macrophages.
Journal of lipid research - 1 Feb 2007
Gille Christian, Spring Bärbel, Bernhard Wolfgang, Gebhard Caroline, Basile Denise, Lauber Kirsten, Poets Christian F, Orlikowsky Thorsten W
Abstract excerpt
Blood monocyte-derived macrophages invading the alveolus encounter pulmonary surfactant, a phospholipoprotein complex that changes composition during lung development. We tested the hypothesis that characteristic phosphatidylcholine (PC) components differentially influence macrophage phenotype and function, as determined by phagocytosis of green fluorescent protein-labeled Escherichia coli and alphaCD3-induced T...
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