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Article

Normal surfactant pool sizes and inhibition-resistant surfactant from mice that overexpress surfactant protein A.

American journal of respiratory cell and molecular biology - 1 Sept 1999

Elhalwagi B M, Zhang M, Ikegami M, Iwamoto H S, Morris R E, Miller M L, Dienger K, McCormack F X

Abstract excerpt

Pulmonary surfactant protein-A (SP-A) has been reported to regulate the uptake and secretion of surfactant by alveolar type II cells, to stabilize large surfactant aggregates including tubular myelin, and to protect the surface activity of surfactant from protein inhibitors. In this study we investigated the consequences of overexpression of SP-A on pulmonary homeostasis and surfactant function in transgenic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10460755
DOI: 10.1165/ajrcmb.21.3.3676

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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