Article
Molecular markers and genetics in cancer development.
Surgical oncology clinics of North America - 1 Jul 2009
Hormi-Carver Kathy, Souza Rhonda F
Abstract excerpt
This article focuses on the conceptual basis underlying the acquisition of each of the physiologic cancer hallmarks by metaplastic Barrett's cells. The acquired genetic alterations that have shown the most promise as potential molecular biomarkers to predict neoplastic progression in patients with Barrett's esophagus are reviewed. Moreover, the role of stem cells and stem cell markers in Barrett's carcinogenesis...
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