Article
Alterations of sodium channel kinetics and gene expression in the postinfarction remodeled myocardium.
Journal of cardiovascular electrophysiology - 1 Feb 2001
Huang B, El-Sherif T, Gidh-Jain M, Qin D, El-Sherif N
Abstract excerpt
INTRODUCTION: After a myocardial infarction (MI), the heart undergoes a remodeling process that includes hypertrophy of noninfarcted left ventricular myocytes. Alterations in the genetic expression, including reexpression of fetal isogene patterns, can result in electrophysiologic changes that contribute to the arrhythmogenicity of post-MI heart. The present study investigated possible alterations in gene...
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