Article
Modulation of cardiac Na+ current phenotype by beta1-subunit expression.
Circulation research - 24 Aug 1998
Kupershmidt S, Yang T, Roden D M
Abstract excerpt
Na+ current (INa) is smaller, activates and inactivates more slowly, and displays less negative voltage dependence of inactivation in the neonatal rat than in the adult rat. We have observed very similar changes when INa is recorded as a function of time in culture in mouse atrial tumor (AT-1) ce...
Topics
- Animals
- Cell Differentiation
- Electrocardiography
- Female
- Heart Atria
- Heart Neoplasms
- Mice
- Mice, Inbred Strains
- Neoplasm Transplantation
- Phenotype
- Rats
- Sodium Channels
- Tumor Cells, Cultured
