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Article

C825T polymorphism of the G protein beta(3)-subunit and antihypertensive response to a thiazide diuretic.

Hypertension (Dallas, Tex. : 1979) - 1 Feb 2001

Turner S T, Schwartz G L, Chapman A B, Boerwinkle E

Abstract excerpt

The T allele of the C825T polymorphism of the gene encoding the beta(3)-subunit of G proteins has been associated with increased sodium-hydrogen exchange and low renin in patients with essential hypertension. To assess its association with blood pressure response to diuretic therapy, we measured the C825T polymorphism in 197 blacks (134 men, 63 women) and 190 non-Hispanic whites (76 men, 114 women) with essential...

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Identifiers

PMID: 11230366
DOI: 10.1161/01.hyp.37.2.739

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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