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Article

G-protein beta-3 subunit gene C825 T polymorphism: influence on plasma sodium and potassium concentrations in essential hypertensive patients.

Life sciences - 21 Oct 2005

Martín Dolores Nieto, Andreu Encarnación Pamies, Ramírez Lorca Reposo, García-Junco Pablo Stiefel, Vallejo Maroto Ignacio, Santos Reyes Aparicio, Miranda Guisado María Luisa, Grijalvo Ovidio Muñiz, Ortiz José Villar, Carneado de la Fuente Joaquín

Abstract excerpt

The C825T polymorphism of the beta-3 subunit of the protein G (GNB3) has been related to an increased activity of the Na+/H+ exchanger (NHE-1) through the synthesis of an anomalous hyperactive protein. Because of the important role of this system in essential hypertension (EH), we analysed the distribution of the different genotypes of this polymorphism in normotensive subjects (NS) and essential hypertensive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16002097
DOI: 10.1016/j.lfs.2005.02.030

Genes

GNB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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