Influence of G-protein β-Polypeptide 3 C825T Polymorphism on Antihypertensive Response to Telmisartan and Amlodipine in Chinese Patients.

doi:10.4103/0366-6999.172548

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Article

Influence of G-protein β-Polypeptide 3 C825T Polymorphism on Antihypertensive Response to Telmisartan and Amlodipine in Chinese Patients.

Chinese medical journal - 5 Jan 2016

Zhang Zan-Lin, Li Hui-Lan, Wen Zhi-Peng, Yang Guo-Ping, Zhang Wei, Chen Xiao-Ping

Abstract excerpt

BACKGROUND: G-protein β-polypeptide 3 (GNB3) is a β subunit isoform of G-protein that plays important role in signal transduction of membrane G-protein coupled receptors (GPCRs). The GNB3 splice variant C825T (rs5443) is associated with risk for essential hypertension (EH) and efficacy of therapeutic drugs targeting GPCRs. It is unknown whether the polymorphism is associated with blood pressure (BP) response to...

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Identifiers

PMID: 26712426
DOI: 10.4103/0366-6999.172548
PMCID: PMC4797547

Genes

GNB3
DBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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