Article
GNB3 C825T and ACE I/D polymorphisms on the sodium-proton exchanger and the prevalence of essential hypertension in males.
Archives of medical research - 1 Jan 2006
Kedzierska Karolina, Ciechanowski Kazimierz, Safranow Krzysztof, Bober Joanna, Gołembiewska Edyta, Kwiatkowska Ewa, Kabat-Koperska Joanna, Ostrowski Marek, Adler Graźyna, Chlubek Dariusz
Abstract excerpt
BACKGROUND: The aim of the study was to verify the hypothesis if the interaction between the G protein beta3 subunit (GNB3) C825T polymorphism and ACE I/D polymorphism could lead to the disclosure of increased activity of sodium-proton exchanger and hypertension. METHODS: The study included 44 male patients, median age: 40 years. Patients were divided into two groups: 26 patients with essential hypertension (EH),...
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