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Article

The Relationship Between Spontaneous Telomere Loss and Chromosome Instability in a Human Tumor Cell Line

1 Jan 2000

Abstract excerpt

Chromosome instability plays an important role in cancer by promoting the alterations in the genome required for tumor cell progression. The loss of telomeres that protect the ends of chromosomes and prevent chromosome fusion has been proposed as one mechanism for chromosome instability in cancer cells, however, there is little direct evidence to support this hypothesis. To investigate the relationship between...

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Identifiers

PMID: 11228547
DOI: 10.1038/sj.neo.7900107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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