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Article

Fusion of a Sequence from HEI10 (14q11) to the HMGIC Gene at 12ql5 in a Uterine Leiomyoma

1 Feb 2001

Abstract excerpt

Uterine leiomyoma, a benign smooth-muscle tumor of the myometrium, is the most commonly encountered neoplasm in women of reproductive age. Band q15 of chromosome 12 is often rearranged in benign mesenchymal tumors such as uterine leiomyomas, and the HMGIC gene, encoding a protein of the high-mobility-group (HMG), is present in that region. Using 3' rapid amplification of cDNA ends (3'RACE) experiments, we...

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Identifiers

PMID: 11223542
DOI: 10.1111/j.1349-7006.2001.tb01075.x

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fusion of a Sequence from HEI10 (14q11) to the HMGIC Gene at 12ql5 in a Uterine LeiomyomaPMID 11223542Read ↗

Three aberrant splicing variants of the HMGIC gene transcribed in uterine leiomyomas.Semantic proximity Read ↗

Evidence forRAD51L1/HMGIC fusion in the pathogenesis of uterine leiomyomaSemantic proximity Read ↗

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HMGIC expression in human adult and fetal tissues and in uterine leiomyomataSemantic proximity Read ↗

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HMGIC alterations in smooth muscle tumors of soft tissues and other sites.Semantic proximity Read ↗

Overexpression of the truncated form of High Mobility Group A proteins (HMGA2) in human myometrial cells induces leiomyoma-like tissue formationSemantic proximity Read ↗

Overexpression of <i>HMGA2</i> in uterine leiomyomas points to its general role for the pathogenesis of the diseaseSemantic proximity Read ↗

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