Article
Characterization of high-level fluoroquinolone resistance in Escherichia coli O78:K80 isolated from turkeys.
The Journal of antimicrobial chemotherapy - 1 Mar 2001
Giraud E, Leroy-Sétrin S, Flaujac G, Cloeckaert A, Dho-Moulin M, Chaslus-Dancla E
Abstract excerpt
Fluoroquinolone resistance was characterized in Escherichia coli O78:K80 isolated from diseased turkeys. The level of resistance to fluoroquinolones of the isolates appeared closely correlated with substitutions in GyrA and ParC, but not with the production of the AcrAB efflux pump. Among isolates highly resistant to ciprofloxacin (MIC 8 mg/L) and harbouring identical substitutions (two in GyrA and one in ParC),...
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