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Article

gyrA mutations in high-level fluoroquinolone-resistant clinical isolates of Escherichia coli.

The Journal of antimicrobial chemotherapy - 1 Sept 1996

Conrad S, Oethinger M, Kaifel K, Klotz G, Marre R, Kern W V

Abstract excerpt

Double mutations in the quinolone resistance determining region of the gyrase A gene (gyrA) have recently been reported to be associated with high-level resistance to fluoroquinolones in clinical isolates of Escherichia coli. We examined the type and frequency of such mutations in a large number of clinical isolates that were obtained from ten different geographical locations and had been genotypically...

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Identifiers

PMID: 8889719
DOI: 10.1093/jac/38.3.443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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