Article
Molecular analysis of fluoroquinolone-resistant Salmonella Paratyphi A isolate, India.
Emerging infectious diseases - 1 Mar 2006
Nair Satheesh, Unnikrishnan Madhulika, Turner Keith, Parija Subash Chandra, Churcher Carol, Wain John, Harish Narasimha
Abstract excerpt
Salmonella enterica serovar Paratyphi A is increasingly a cause of enteric fever. Sequence analysis of an Indian isolate showed a unique strain with high-level resistance to ciprofloxacin associated with double mutations in the DNA gyrase subunit gyrA (Ser83-->Phe and Asp87-->Gly) and a mutation in topoisomerase IV subunit parC (Ser80-->Arg).
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