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Article

Glycophosphatidylinositol-anchored protein deficiency as a marker of mutator phenotypes in cancer.

Cancer research - 15 Jan 2001

Chen R, Eshleman J R, Brodsky R A, Medof M E

Abstract excerpt

Phosphatidylinositol glycan-A (PIGA) is a gene that encodes an element required for the first step in glycosylphosphatidylinositol (GPI) anchor assembly. Because PIGA is X-located, a single mutation is sufficient to abolish cell surface GPI-anchored protein expression. In this study, we investiga...

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Source

Identifiers

PMID: 11212264

Genes

GPI
PIGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11212264-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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