Article
Alcohol ingestion and colorectal neoplasia: a meta-analysis based on a Mendelian randomization approach.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland - 1 May 2011
Wang J, Wang H, Chen Y, Hao P, Zhang Y
Abstract excerpt
AIM: Observed associations of alcohol with colorectal cancer are prone to distortion by confounding and reverse causation. A Mendelian randomization approach provides an unbiased estimate of the association using the aldehyde dehydrogenase 2 (ALDH2) variant as a surrogate of alcohol exposure. MET...
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