Gene expression of the human glucagon-like peptide-1 receptor is regulated by Sp1 and Sp3.

doi:10.1210/endo.140.2.6512

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Article

Gene expression of the human glucagon-like peptide-1 receptor is regulated by Sp1 and Sp3.

Endocrinology - 1 Feb 1999

Wildhage I, Trusheim H, Göke B, Lankat-Buttgereit B

Abstract excerpt

The human glucagon-like peptide-1 (GLP-1) receptor mediates the insulinotropic effects of the incretin hormone GLP-1. It is expressed in a cell- and tissue-specific manner. Recently, we cloned the 5'-region of the GLP-1 receptor gene and found that tissue and cell specificity is lost by 5'-deleti...

Topics

Animals
Base Sequence
Binding Sites
Blotting, Western
Cell Line
DNA Footprinting
DNA-Binding Proteins
Drosophila melanogaster
Electrophoresis
Gene Expression Regulation
Glucagon-Like Peptide-1 Receptor
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Plasmids

Promoter Regions, Genetic

Receptors, Glucagon

Sp1 Transcription Factor

Source

Open in PubMed

Identifiers

PMID: 9927286
DOI: 10.1210/endo.140.2.6512

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9927286-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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