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Article

Epigenetic regulation of SST2 expression in small intestinal neuroendocrine tumors

8 May 2023

Abstract excerpt

Background Somatostatin receptor type 2 (SST 2 ) expression is critical for the diagnosis and treatment of neuroendocrine tumors and is associated with improved patient survival. Recent data suggest that epigenetic changes such as DNA methylation and histone modifications play an important role in regulating SST 2 expression and tumorigenesis of NETs. However, there are limited data on the association between...

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PMID: 37223009
DOI: 10.3389/fendo.2023.1184436

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