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Article

Salmonella typhimurium mutants that downregulate phagocyte nitric oxide production.

Cellular microbiology - 1 Jun 2000

Eriksson S, Björkman J, Borg S, Syk A, Pettersson S, Andersson D I, Rhen M

Abstract excerpt

To examine the potential and strategies of the facultative intracellular pathogen Salmonella typhimurium to increase its fitness in host cells, we applied a selection that enriches for mutants with increased bacterial growth yields in murine J774-A.1 macrophage-like cells. The selection, which was based on intracellular growth competition, rapidly yielded isolates that out-competed the wild-type strain during...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11207580
DOI: 10.1046/j.1462-5822.2000.00051.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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