Article
The role of DNA base excision repair in the pathogenesis of Salmonella enterica serovar Typhimurium.
Molecular microbiology - 1 Apr 2003
Suvarnapunya Akamol E, Lagassé H A Daniel, Stein Murry A
Abstract excerpt
The intracellular pathogen, Salmonella enterica serovar Typhimurium, is able to proliferate in phagocytes, although reactive oxygen and nitrogen intermediates are lethal to most phagocytosed bacteria. To determine whether repair of oxidatively damaged DNA is involved in S. typhimurium intramacrophage proliferation, null mutants of the DNA base excision repair (BER) system were generated. These mutants were...
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