Article
Phenotypical changes of a human pancreatic adenocarcinoma cell line after selection on laminin-1/nidogen (LM/Ng) substratum.
European journal of cell biology - 1 Aug 1998
Paddenberg R, Flocke K, Elsässer H P, Lesch G, Heidtmann H H, Mannherz H G
Abstract excerpt
A cell line (PaTu 8902LM) exhibiting an altered phenotypic appearance was selected from a highly dedifferentiated established human pancreatic tumour cell line (PaTu 8902) by repetitive exposure to laminin-1/nidogen substratum and subsequent selection for adherent cells. Polymerase chain reaction...
Topics
- Adenocarcinoma
- Animals
- Antineoplastic Agents, Phytogenic
- Cell Adhesion
- Cell Membrane
- Cell Polarity
- Chromosomes
- Colchicine
- Cytoskeleton
- Endopeptidases
- Extracellular Matrix
- Fluorescent Antibody Technique
- Gene Expression Regulation, Neoplastic
- Humans
- Laminin
- Membrane Glycoproteins
- Mice
- Mice, Nude