Article
Phenotypical changes of a human pancreatic adenocarcinoma cell line after selection on laminin-1/nidogen (LM/Ng) substratum.
European journal of cell biology - 1 Aug 1998
Paddenberg R, Flocke K, Elsässer H P, Lesch G, Heidtmann H H, Mannherz H G
Abstract excerpt
A cell line (PaTu 8902LM) exhibiting an altered phenotypic appearance was selected from a highly dedifferentiated established human pancreatic tumour cell line (PaTu 8902) by repetitive exposure to laminin-1/nidogen substratum and subsequent selection for adherent cells. Polymerase chain reaction analysis for repetitive DNA indicated that both cell lines are genetically very closely related. The original PaTu...
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