Article
Optimal peeling order for pedigrees with incomplete genotypic information.
Computational biology and chemistry - 1 Jun 2007
Belonogova Nadezhda M, Axenovich Tatiana I
Abstract excerpt
The likelihood approach is common in linkage analysis of large extended pedigrees. Various peeling procedures, based on the conditional independence of separate parts of a pedigree, are typically used for likelihood calculations. A peeling order may significantly affect the complexity of such calculations, particularly for pedigrees with loops or when many pedigrees members have unknown genotypes. Several...
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