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Article

Effect of calcimimetic agent, KRN568, on gastrin secretion in healthy subjects.

Endocrine journal - 1 Oct 2000

Igarashi T, Ogata E, Maruyama K, Fukuda T

Abstract excerpt

KRN568 is a calcimimetic compound which acts on the calcium sensing receptors (CaR) on the parathyroid gland to suppress secretion of PTH. A recent report has demonstrated that CaRs are expressed on cultured human antral gastrin cells and that gastrin secretion is stimulated by an increase in extracellular calcium level. However, the effect of KRN568 on serum gastrin levels has yet to be clinically assessed. We...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11200930
DOI: 10.1507/endocrj.47.517

Genes

PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effect of calcimimetic agent, KRN568, on gastrin secretion in healthy subjects.PMID 11200930Read ↗

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