Article
CTLA-4 and CD86 genetic variants and haplotypes in patients with rheumatoid arthritis in southeastern China.
Genetics and molecular research : GMR - 25 Apr 2013
Liu C-P, Jiang J-A, Wang T, Liu X-M, Gao L, Zhu R-R, Shen Y, Wu M, Xu T, Zhang X-G
Abstract excerpt
The cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and costimulatory molecule (CD80/CD86) genes are important susceptibility genes associated with autoimmune diseases. CTLA-4 polymorphisms have been found to be associated with various autoimmune diseases. However, the association data are inconsistent for rheumatoid arthritis (RA). We investigated the genetic association of CTLA-4 and CD86 polymorphisms...
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