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Article

CD28 Genetic Variants Increase Susceptibility to Diabetic Kidney Disease in Chinese Patients with Type 2 Diabetes: A Cross-Sectional Case Control Study.

Mediators of inflammation - 1 Jan 2021

Li Yangyang, Jin Li, Yan Jing, Zhang Hong, Zhang Rong, Hu Cheng

Abstract excerpt

Few studies have illuminated the genetic role of T cell costimulatory molecule CD28/CD80/CTLA4 variants in diabetic kidney disease (DKD) susceptibility. We aimed to investigate the causal role of genetic polymorphisms in CD28/CD80/CTLA4 with DKD susceptibility in patients with T2DM. A total of 3253 patients with T2DM were recruited for genotyping: including 204 DKD patients and 371 controls in stage 1 and 819 DKD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33958973
DOI: 10.1155/2021/5521050
PMCID: PMC8075672

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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