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Article

Molecular pathogenesis of long QT syndrome type 2

22 Jan 2016

Abstract excerpt

Abstract The molecular mechanisms underlying congenital long QT syndrome (LQTS) are now beginning to be understood. New insights into the etiology and therapeutic strategies are emerging from heterologous expression studies of LQTS‐linked mutant proteins, as well as inducible pluripotent stem cell derived cardiomyocytes (iPSC‐CMs) from LQTS patients. This review focuses on the major molecular mechanism that...

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PMID: 27761161
DOI: 10.1016/j.joa.2015.11.009

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