Article
Congenital long QT syndromes: clinical features, molecular genetics and genetic testing.
Expert review of molecular diagnostics - 1 May 2006
Ching Chi-Keong, Tan Ene-choo
Abstract excerpt
Congenital long QT syndrome (LQTS) is a primary electrical disease characterized by a prolonged QT interval in the surface electrocardiogram and increased predisposition to a typical polymorphic ventricular tachycardia, termed Torsade de Pointes. Most patients with LQTS are asymptomatic and are diagnosed incidentally based on an electrocardiogram. Symptomatic patients may suffer from severe cardiac events, such...
Topics
- Ether-A-Go-Go Potassium Channels
- Genes, Dominant
- Genes, Recessive
- Genetic Predisposition to Disease
- Genetic Techniques
- Genetic Testing
- Heterozygote
- Homozygote
- Humans
- Long QT Syndrome
- Molecular Biology