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Aborted Cardiac Arrest in LQT2 Related to Novel KCNH2 (hERG) Variant Identified in One Lithuanian Family.

Medicina (Kaunas, Lithuania) - 16 Jul 2021

Bileišienė Neringa, Barysienė Jūratė, Mikštienė Violeta, Preikšaitienė Eglė, Marinskis Germanas, Keževičiūtė Monika, Utkus Algirdas, Aidietis Audrius

Abstract excerpt

Congenital long QT syndrome (LQTS) is a hereditary ion channelopathy associated with ventricular arrhythmia and sudden cardiac death starting from young age due to prolonged cardiac repolarization, which is represented by QT interval changes in electrocardiogram (ECG). Mutations in human ether-à-go-go related gene (KCNH2 (7q36.1), formerly named hERG) are responsible for Long QT syndrome type 2 (LQT2). LQT2 is...

Topics

Adult
Death, Sudden, Cardiac
ERG1 Potassium Channel
Ether-A-Go-Go Potassium Channels
Heart Arrest
Humans
Long QT Syndrome
Male
Mutation

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Identifiers

PMID: 34357002
DOI: 10.3390/medicina57070721
PMCID: PMC8305506

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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