Article
Age-associated accumulation of the apolipoprotein C-III gene T-455C polymorphism C allele in a Russian population.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Jan 2001
Anisimov S V, Volkova M V, Lenskaya L V, Khavinson V K, Solovieva D V, Schwartz E I
Abstract excerpt
Apolipoprotein C-III (apoC-III) is the major component of triglyceride-rich lipoproteins. One of six identified polymorphisms in the apoC-III 5'-untranslated region (T-455C) is located within a functional insulin-response element. In a group of 137 elderly individuals (70-106 years old), the allele distribution was analyzed using restriction fragment length polymorphisms. Statistical analysis of allele...
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