Article
Association of the apolipoprotein A-IV: 360 Gln/His polymorphism with cerebrovascular disease, obesity, and depression in a Brazilian elderly population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 May 2005
Ejchel T F, Araújo L M Q, Ramos L R, Cendoroglo M S, de Arruda Cardoso Smith Marília
Abstract excerpt
The identification of genetic polymorphisms as risk factors for complex diseases can be relevant for their prevention, diagnosis, and prognosis. The apolipoprotein A-IV: 360 Gln/His polymorphism was investigated in 383 elderly individuals, who were participants of a longitudinal study commenced in 1991. The major morbidities that affect elderly people, such as cardiovascular diseases, diabetes, low cognitive...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Amino Acid Substitution
- Apolipoproteins A
- Brazil
- Cerebrovascular Disorders
- Depressive Disorder
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype