Apolipoprotein AIV codon 360 mutation increases with human aging and is not associated with Alzheimer's disease.

doi:10.1016/s0304-3940(98)00025-1

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Article

Apolipoprotein AIV codon 360 mutation increases with human aging and is not associated with Alzheimer's disease.

Neuroscience letters - 13 Feb 1998

Merched A, Xia Y, Papadopoulou A, Siest G, Visvikis S

Abstract excerpt

In order to evaluate genetic apolipoprotein polymorphisms as risk factors for Alzheimer's disease (AD), we studied apolipoprotein (apo) AIV after apoE, an apolipoprotein also present in the brain. The allelic distribution of apoAIV codon 360 polymorphism was no different in AD group (n = 120) com...

Topics

Aged
Aged, 80 and over
Aging
Alleles
Alzheimer Disease
Apolipoproteins A
Female
Gene Frequency
Genetic Markers
Genotype
Humans
Male
Middle Aged
Point Mutation
Polymorphism, Genetic

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