Article
Electrophoretic screening for genetic variation in apolipoprotein C-III: identification of a novel apoC-III variant, apoC-III(Asp45-->Asn), in a Turkish patient.
Journal of lipid research - 1 Aug 1994
Lüttmann S, von Eckardstein A, Wei W, Funke H, Köhler E, Mahley R W, Assmann G
Abstract excerpt
Screening of 6,840 plasma samples by isoelectric focusing (IEF) led to the identification of a novel apolipoprotein C-III variant. The underlying molecular defect was established by sequencing of exons 3 and 4 of the apoC-III gene subsequent to their amplification by the polymerase chain reaction...
Topics
- Alleles
- Apolipoproteins C
- Base Sequence
- Genetic Testing
- Germany
- Haplotypes
- Humans
- Lipoproteins, LDL
- Lipoproteins, VLDL
- Male
- Middle Aged
- Molecular Sequence Data
- Pedigree
- Reference Values
- Turkey