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Tetraspanins and vascular functions

27 Feb 2009

Abstract excerpt

Tetraspanins are multiple membrane-spanning proteins that likely function as the organizers of membrane microdomains. Tetraspanins associate with other membrane-bound molecules such as cell-adhesion proteins, growth factor receptors, and Ig superfamily members and regulate key cellular processes such as adhesion, migration, and fusion. Tetraspanins are widely expressed in vascular and haematopoietic cells and are...

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PMID: 19251723
DOI: 10.1093/cvr/cvp080

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