Article
Pneumococcal Adhesins PavB and PspC Are Important for the Interplay with Human Thrombospondin-1
21 Apr 2015
Abstract excerpt
The human matricellular glycoprotein thrombospondin-1 (hTSP-1) is released by activated platelets and mediates adhesion of Gram-positive bacteria to various host cells. In staphylococci, the adhesins extracellular adherence protein (Eap) and autolysin (Atl), both surface-exposed proteins containing repeating structures, were shown to be involved in the acquisition of hTSP-1 to the bacterial surface. The...
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