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Article

Psidin, a conserved protein that regulates protrusion dynamics and cell migration.

Genes & development - 1 Apr 2011

Kim Ji Hoon, Cho Aeri, Yin Hongyan, Schafer Dorothy A, Mouneimne Ghassan, Simpson Kaylene J, Nguyen Kim-Vy, Brugge Joan S, Montell Denise J

Abstract excerpt

Dynamic assembly and disassembly of actin filaments is a major driving force for cell movements. Border cells in the Drosophila ovary provide a simple and genetically tractable model to study the mechanisms regulating cell migration. To identify new genes that regulate cell movement in vivo, we screened lethal mutations on chromosome 3R for defects in border cell migration and identified two alleles of the gene...

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Identifiers

PMID: 21406550
DOI: 10.1101/gad.2028611
PMCID: PMC3070935

Genes

EGF

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