High-resolution minisatellite-based typing as a portable approach to global analysis of <i>Mycobacterium tuberculosis</i> molecular epidemiology

Abstract excerpt

The worldwide threat of tuberculosis to human health emphasizes the need to develop novel approaches to a global epidemiological surveillance. The current standard for Mycobacterium tuberculosis typing based on IS6110 restriction fragment length polymorphism (RFLP) suffers from the difficulty of comparing data between independent laboratories. Here, we propose a high-resolution typing method based on variable...

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