Article
Proposal for standardization of optimized mycobacterial interspersed repetitive unit-variable-number tandem repeat typing of Mycobacterium tuberculosis.
Journal of clinical microbiology - 1 Dec 2006
Supply Philip, Allix Caroline, Lesjean Sarah, Cardoso-Oelemann Mara, Rüsch-Gerdes Sabine, Willery Eve, Savine Evgueni, de Haas Petra, van Deutekom Henk, Roring Solvig, Bifani Pablo, Kurepina Natalia, Kreiswirth Barry, Sola Christophe, Rastogi Nalin, Vatin Vincent, Gutierrez Maria Cristina, Fauville Maryse, Niemann Stefan, Skuce Robin, Kremer Kristin, Locht Camille, van Soolingen Dick
Abstract excerpt
Molecular typing based on 12 loci containing variable numbers of tandem repeats of mycobacterial interspersed repetitive units (MIRU-VNTRs) has been adopted in combination with spoligotyping as the basis for large-scale, high-throughput genotyping of Mycobacterium tuberculosis. However, even the combination of these two methods is still less discriminatory than IS6110 fingerprinting. Here, we define an optimized...
Topics
- Bacterial Typing Techniques
- Cluster Analysis
- DNA Fingerprinting
- DNA Transposable Elements
- DNA, Bacterial
- Genotype
- Humans
- Interspersed Repetitive Sequences
