Article
Linkage disequilibrium between minisatellite loci supports clonal evolution of Mycobacterium tuberculosis in a high tuberculosis incidence area.
Molecular microbiology - 1 Jan 2003
Supply Philip, Warren Robin M, Bañuls Anne-Laure, Lesjean Sarah, Van Der Spuy Gian D, Lewis Lee-Anne, Tibayrenc Michel, Van Helden Paul D, Locht Camille
Abstract excerpt
Deciphering the structure of pathogen populations is instrumental for the understanding of the epidemiology and history of infectious diseases and for their control. Although Mycobacterium tuberculosis is the most widespread infectious agent in humans, its actual population structure has remained hypothetical until now because: (i) its structural genes are poorly polymorphic; (ii) adequate samples and appropriate...
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