Evaluation and strategy for use of MIRU-VNTRplus, a multifunctional database for online analysis of genotyping data and phylogenetic identification of Mycobacterium tuberculosis complex isolates.

Abstract excerpt

Because of its portable data, discriminatory power, and recently proposed standardization, mycobacterial interspersed repetitive-unit-variable-number tandem-repeat (MIRU-VNTR) typing has become a major method for the epidemiological tracking of Mycobacterium tuberculosis complex (MTBC) clones. However, no public MIRU-VNTR database based on well-characterized reference strains has been available hitherto for easy...

Topics

• Bacterial Typing Techniques
• Cluster Analysis
• DNA Fingerprinting
• DNA, Bacterial
• Databases, Genetic
• Genotype
• Humans
• Interspersed Repetitive Sequences
• Microbial Sensitivity Tests
• Molecular Epidemiology