Article
Stability of variable-number tandem repeats of mycobacterial interspersed repetitive units from 12 loci in serial isolates of Mycobacterium tuberculosis.
Journal of clinical microbiology - 1 Dec 2002
Savine Evgueni, Warren Robin M, van der Spuy Gian D, Beyers Nulda, van Helden Paul D, Locht Camille, Supply Philip
Abstract excerpt
Variable number tandem repeats (VNTRs) of elements named mycobacterial interspersed repetitive units (MIRUs) have previously been identified in 12 minisatellite loci of the Mycobacterium tuberculosis genome. These markers allow reliable high-throughput genotyping of M. tuberculosis and represent a portable approach to global molecular epidemiology of M. tuberculosis. To assess their temporal stability, we...
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