Article
Catechol-O-methyltransferase and monoamine oxidase B genes and susceptibility to sporadic Parkinson's disease in a Polish population.
European neurology - 1 Jan 2005
Białecka Monika, Droździk Marek, Honczarenko Krystyna, Gawrońska-Szklarz Barbara, Stankiewicz Jan, Dabrowska Ewa, Kubisiak Maciej, Kłodowska-Duda Gabriela, Opala Grzegorz
Abstract excerpt
Recent reports have proved that genetic factors play a role in the pathogenesis of sporadic Parkinson's disease (PD). It has been suggested that polymorphisms in monoamine oxidase B (MAOB) and catechol-O-methyltransferase (COMT) might increase the risk of PD. A total of 210 Polish patients with sporadic PD and 152 healthy controls were studied. The MAOB and COMT polymorphisms were identified using the polymerase...
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