Article
Phenotypic alterations in senescent large-vessel and microvascular endothelial cells.
Molecular cell biology research communications : MCBRC - 1 Aug 2000
Cavallaro U, Castelli V, Del Monte U, Soria M R
Abstract excerpt
Endothelial cell senescence likely plays a key role in age-associated vascular diseases. A close relationship between in vitro and in vivo senescence of endothelial cells has been established. Therefore, elucidating the structural and functional changes occurring during long-term cultures of endothelial cells would contribute to clarifying the pathogenesis of vascular disorders in the elderly. We investigated the...
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