Article
Vascular aging: Molecular mechanisms and potential treatments for vascular rejuvenation.
Ageing research reviews - 1 Aug 2017
Mistriotis Panagiotis, Andreadis Stelios T
Abstract excerpt
Aging is the main risk factor contributing to vascular dysfunction and the progression of vascular diseases. In this review, we discuss the causes and mechanisms of vascular aging at the tissue and cellular level. We focus on Endothelial Cell (EC) and Smooth Muscle Cell (SMC) aging due to their critical role in mediating the defective vascular phenotype. We elaborate on two categories that contribute to cellular...
Topics
- Aging
- Animals
- Cellular Senescence
- Endothelial Cells
- Genetic Therapy
- Humans
- Muscle, Smooth, Vascular
- Myocytes, Smooth Muscle
- Phenotype
- Rejuvenation
- Stem Cell Transplantation
